Abstract
Objective: To evaluate serum total cholesterol (TC) and malondialdehyde (MDA) in
healthy subjects in winter and summer seasons.
Subjects and methods: This study was conducted at the college of Pharmacy,
University of Mosul. Twenty healthy subjects, non-smokers, free from any
medication were included in this study. Five mL of blood sample from each subject
was taken in winter and other blood sample was taken from the same subject in
summer and analysed for serum TC and MDA.
Results: No significant difference was noticed between winter and summer for serum
TC (٤.٦٥±٠.٥٩ mmol/L versus ٤.٤٥±٠.٦ mmol/L). However, serum MDA in
summer (١.١٩±٠.٢ µmole/L) was significantly higher (P < ٠.٠١) than in winter
(٠.٩٦±٠.١٦ µmol/L)
Conclusion: Oxidative stress increases in hot weather. Seasonal serum lipid profile
levels depend on life style of the people and their geographical location.
