Abstract
The inhibitory effect of a number of locally used organophosphorus and carbamate insecticides on human plasma
and erythrocyte were examined in vitro by using the modified electrometric method for determination of
cholinesterase (ChE) activity. The negative logarithum of inhibitor concentration required for 50% inhibition
(pIC50) was estimated to range between -12.6 to 2.4 and between - 8.5 to - 0.77 for plasma and erythrocyte ChE,
respectively. Plasma ChE was more susceptible than erythrocyte ChE to effects of the insecticides. Thermal
reactivation technique was applied on plasma and erythrocyte ChE to identify and differentiate between
organophosphorus and carbamate insecticides
