Synthetic Cannabinoid Receptor Agonist ‘JWH-018’ does not mimic Serotonin

Adam J. Pottsa; Israa M. Albanaa; Sarah E. Gartsidec; Peter S. Hansonb; Simon L. Hilld; Simon H. Thomasb; Sarah J. Judgec

Volume 19, Issue 1 , July 2022, Page 1-7

https://doi.org/10.33899/iphr.2022.174794

Abstract
  Synthetic cannabinoid receptor agonists (SCRAs) are popular recreational drugs. It has been suggested that indole-containing SCRAs may have activity at several serotonergic targets, owing to their structural similarity to the neurotransmitter serotonin (5-HT). This similarity may be responsible for features ...  Read More ...

Synthesis, mechanism of action, and structure-activity relationships of 1,3-oxazolidinones as anti-bacterial Agent: A review

Ali M. Hantosh; Nawal Rajab; Faris Abachi

Volume 19, Issue 1 , July 2022, Page 8-16

https://doi.org/10.33899/iphr.2022.174796

Abstract
  Background: 1,3-oxazolidinones are an important class of antibiotics that are recognized with higher activities against Gram-positive bacteria. linezolid, tedizolid phosphate, and radezolid are important examples of this group. Aim: The aim of this review is to study the effect of 1,3-oxazolidinone derivatives ...  Read More ...

Evaluation of serum lipid profile in breast cancer patients: a case control study

Shahbaa A. Al-bayati

Volume 19, Issue 1 , July 2022, Page 17-22

https://doi.org/10.33899/iphr.2022.174797

Abstract
  Objective: This study was conducted to investigate the relationship between serum lipid profile and breast cancer disease.Patients and methods: One hundred breast cancer women and 75 women with benign breast mass as a control group were included in the study. The control and the patient groups were aged ...  Read More ...

The Efficacy of Azelaic Acid 20% Cream in the Treatment of Scalp Alopecia Areata

Mudheher I. Salih; Dindar S. Qurtas

Volume 19, Issue 1 , July 2022, Page 23-33

https://doi.org/10.33899/iphr.2022.174798

Abstract
  Introduction: Alopecia areata is a common, inflammatory, non-scarring type of hair loss that affects persons of both sexes and all age groups, with prevalence in the general population of approximately 0.1–0.2%. It is characterized by variable clinical presentations, ranging from single or multiple ...  Read More ...

Prevalence of Non-Scarring Alopecia among Female Patients Complaining from Hirsutism

Salar O. Awrahman; Dindar S. Qurtas

Volume 19, Issue 1 , July 2022, Page 34-46

https://doi.org/10.33899/iphr.2022.174799

Abstract
  Background: Hirsutism is a common clinical problem that cause great distress to the patient, and which true incidence is unknown. However, it is more common among Mediterranean women. Hirsutism is excessive terminal hair growth in women in androgen-dependent. Often the cause of it is hyperandrogenism ...  Read More ...

Evaluation of serum zinc level in patients with Alopecia Areata

Ivan Abdullah; Sangar Othman

Volume 19, Issue 1 , July 2022, Page 47-53

https://doi.org/10.33899/iphr.2022.174800

Abstract
  Background: Alopecia areata (AA) is non-scarring telogenic alopecia of autoimmune etiology. Clinically, the disease is characterized by the appearance of alopecic patches or plaques of varying size and number on the scalp with peak incidence 2% in the general population, can involve any age group with ...  Read More ...

Intradermal injection of tranexamic acid combined with topical hydroquinone cream versus topical hydroquinone cream alone in the treatment of melasma

Lavan Y. Taha; Pers Y. Sheer

Volume 19, Issue 1 , July 2022, Page 54-64

https://doi.org/10.33899/iphr.2022.174801

Abstract
  Background: Melasma is a common acquired skin disorder that presents as a bilateral, blotchy, brownish facial pigmentation due to a dysfunction in melanogenesis. It is most common in people who tans easily or have naturally brown skin (Fitzpatrick’s skin phototypes III, IV). Although ...  Read More ...

Topical Imiquimod 5% Cream Versus Salicylic acid 30% Cream in Treating Common Warts: A comparative study

Dilpak N. Muhammed-Ameen; Alan D. Meran

Volume 19, Issue 1 , July 2022, Page 65-79

https://doi.org/10.33899/iphr.2022.174802

Abstract
  Background: Warts are considered the foremost common infectious diseases affecting the epidermal keratinocytes, the causative agent is the human papilloma virus (HPV). Diagnosis usually can be confirmed depending on both the clinical features and family history. Although these viruses create no acute ...  Read More ...

Drug-Induced Nephrotoxicity: A Review

Muthanna T. Khalaf; Zeina A. Althanoon

Volume 19, Issue 1 , July 2022, Page 80-89

https://doi.org/10.33899/iphr.2022.174803

Abstract
  Background: Nephrotoxicity is referred to as rapid degeneration in kidney functioning due to the toxic effects of medications. The glomerulus and proximal renal tubule are the fundamental portions of the nephron to be affected by drugs leading to nephrotoxicity. Prescribed medications like antibiotics ...  Read More ...

Sleep Quality in Diabetic Patients

Israa M. Salih; Harith K. Al-Qazaz

Volume 19, Issue 1 , July 2022, Page 90-97

https://doi.org/10.33899/iphr.2022.174804

Abstract
  Background: Diabetes mellitus (DM) is a metabolic condition characterized by a persistent rise in blood glucose and a disturbance in the body metabolic state. Sleep is essential for survival and the proper functioning of the body. In diabetes, appropriate sleep is important for handling insulin levels, ...  Read More ...

Role of Neurotropic B Vitamins in the Treatment of Diabetic Neuropathy: Narrative Review

Narmin S. Essa; Mohammed I. Aladul

Volume 19, Issue 1 , July 2022, Page 98-111

https://doi.org/10.33899/iphr.2022.174805

Abstract
  Diabetic neuropathy (DN) is the presence of signs and symptoms that are suggestive of neuropathy in diabetic patients, after excluding other possible causes of nerve damage. Diabetic neuropathy and its complications affect the quality of life, sleep patterns, and daily activities of the patient. Up to ...  Read More ...

Health-related quality of life among patients with osteoarthritis: A review of literature

Zahraa S. Thabit; Harith K. Al-Qazaz

Volume 19, Issue 1 , July 2022, Page 112-124

https://doi.org/10.33899/iphr.2022.174806

Abstract
  Background and objective: Osteoarthritis (OA) is a more common disease that effects the joints in the world and it is more prevalent with increasing age, and is most common in old people. Quality of life (QoL) is defined as a set of values and culture that is aligned with an individual's aim and in accordance ...  Read More ...

Anticancer Induced Nephrotoxicity: A Review

Akram A. Hammo; Zeina A. Althanoon; Abdulla A. Ahmad

Volume 19, Issue 1 , July 2022, Page 125-133

https://doi.org/10.33899/iphr.2022.174807

Abstract
  Introduction: Drug-induced adverse effects are the major challenging issue in the clinical setting of chemotherapy. Kidneys are responsible for the elimination of many chemotherapeutic agents which makes them a common target for adverse effects. Nephrotoxicity is a deleterious adverse effect carrying ...  Read More ...

Effects Of Estrogen and Progesterone Used in Oral Contraceptive Pills: A review

Farah R. Noori; Zeina A. Althanoon

Volume 19, Issue 1 , July 2022, Page 134-146

https://doi.org/10.33899/iphr.2022.174808

Abstract
  Introduction Contraception is a method of avoiding unplanned pregnancy. Combined oral contraceptives (COCs) have become a prominent birth control method due to their contraceptive efficacy and acceptability profile. The use of oral contraceptive pills (OCPs) is linked to several health advantages as ...  Read More ...

A Review in the View on Wounds

Zahraa S. Qasim

Volume 19, Issue 1 , July 2022, Page 147-158

https://doi.org/10.33899/iphr.2022.174809

Abstract
  Whatever the etiology of wounds, some heal without difficulties, however in chronic wound the ultimate goal in wounds healing are to control symptoms and prevent complication like infection. The latter occurs when microorganisms of different kinds grow within damaged skin. The sign and symptoms vary ...  Read More ...