Paracetamol/ naproxen co-crystals; a simple way for improvement of flowability, tableting and dissolution properties

Amal Al-Dulaimi; Myasar Al-kotaji; Faris Abachi

Volume 18, Issue 1 , August 2021, Page 1-19

https://doi.org/10.33899/iphr.2021.168798

Abstract
  Background: The poor solubility of drugs is one of the most important limitations in formulating drugs into suitable dosage forms. In addition, the mechanical properties are the main obstacles in formulating tablet dosage form by direct compression method. This study aims to investigate the possible ...  Read More ...

Impact of Selenium on Structural Changes Induced by Hypothyroidism In Adult Male Rat ׳s Testis

Eman Alhealy; Maysoon Alqazzaz; Wahda M. AL-Nuaimy

Volume 18, Issue 1 , August 2021, Page 20-32

https://doi.org/10.33899/iphr.2021.168799

Abstract
  Background: The poor solubility of drugs is one of the most important limitations in formulating drugs into suitable dosage forms. In addition, the mechanical properties are the main obstacles in formulating tablet dosage form by direct compression method. Aim of this research: To investigate the ...  Read More ...

Preparation of Cinnarizine Oral Lyophilizates

Rasha Dhahir; Myasar Al-Kotaji

Volume 18, Issue 1 , August 2021, Page 33-43

https://doi.org/10.33899/iphr.2021.168800

Abstract
  Background: Orally disintegrating tablets (ODTs) have gained an increasing interest in the pharmaceutical industry for the last years. Several technologies have been sophisticated for ODTs to improve patient compliance. In the present work, an attempt has been made to formulate and evaluate cinnarizine, ...  Read More ...

Effect of antibiotic misuse on the emergence of microbial resistance among urologic patients

Maimonah Qasim Yahya; Salah H. Azba; Maali I. Al-Hayali

Volume 18, Issue 1 , August 2021, Page 44-56

https://doi.org/10.33899/iphr.2021.168843

Abstract
  Background: The study aimed to identify the types of bacteria isolated from the urine of patients with urinary tract infections focusing on the resistant isolates then comparing the results with the types of antibiotics misused by those patients in order to suggest some measures to mitigate the increasing ...  Read More ...

The Relationship Between Magnesium Supplementation and Glycemic Control in Diabetic Patients: A Review

Doaa K. Ibrahim; Zeina A. Al-Thanoon

Volume 18, Issue 1 , August 2021, Page 57-66

https://doi.org/10.33899/iphr.2021.168801

Abstract
  Background: Diabetes mellitus is a chronic disease with increasing worldwide prevalence. There are many studies to observe the role of minerals on the glycemic state in diabetic patients. One of the in the human se minerals is magnesium. Magnesium is the fourth most abundant mineral in the human body. ...  Read More ...

The Role of Co-Enzyme Q10 in The Respiratory Chain and Some of Its Clinical Indications: A review

Noor Al-Huda A. Al-Zarqy; Zeina A. Al-Thanoon

Volume 18, Issue 1 , August 2021, Page 67-77

https://doi.org/10.33899/iphr.2021.168802

Abstract
  Background: The usage of supplements becomes an important part of everyone health since many of these materials have produced real improvement in general health. These materials are not approved by organization like Food and Drug Administration in the US and the Food Safety Authority in Europe as drugs ...  Read More ...

Strategies To Enhance Transdermal Drug delivery

Mais S. Saadallah; Omar A. Hamid

Volume 18, Issue 1 , August 2021, Page 78-92

https://doi.org/10.33899/iphr.2021.168803

Abstract
  Background: Transdermal drug delivery system (TDDS) is a promising delivery system that provides controlled drug release at a predetermined time. It has many advantages such as bypassing first-pass effect, increase patient convenience by providing single application rather than multiple dosing frequencies, ...  Read More ...

Nose to brain delivery of drugs for CNS diseases

Zahraa H. Ali; Myasar Alkotaji

Volume 18, Issue 1 , August 2021, Page 93-107

https://doi.org/10.33899/iphr.2021.168804

Abstract
  Background: The management of central nervous system diseases is extremely challenging due to the numerous obstacles that stand against the successful delivery of drugs to their target site in the brain. Defeating the blood-brain barrier is considered the most significant challenge in this delivery. ...  Read More ...

A review of the effect of Coenzyme Q10 in patients with polycystic ovary syndrome

Shahad A. Badr; Zeina A. Althanoon

Volume 18, Issue 1 , August 2021, Page 108-117

https://doi.org/10.33899/iphr.2021.168805

Abstract
  Background: Women with polycystic ovary syndrome are usually suffering from many metabolic disturbances as insulin resistance, so the use of Co enzyme Q10 in those patients improve metabolic changes and insulin resistance resulting in better ovulation.Mitochondrial dysfunction in the eggs is related ...  Read More ...