Evaluation of CA 15-3, Her-2/neu and estrogen/progesterone status in breast cancer patients treated by surgical removal and chemotherapy

Taha H Taha Al-siagh; Shahbaa A Al-bayati; Faris A Ahmed

Volume 12, Issue 1 , December 2012, Page 1-7

https://doi.org/10.33899/iphr.2012.62338

Abstract
  Objective: This study was conducted to evaluate serum CA 15-3 in breast cancer patients after surgery and chemotherapy. The relationship between serum CA 15-3 and Her-2/neu, estrogen, or progesterone receptors were also studied in the breast cancer patients. Patients and methods: This study was conducted ...  Read More ...

Evaluation of combined biochemical markers in the diagnosis of acute coronary syndrome in Nineveh governorate

Samir B Al-mukhtar; Akram J Ahmad

Volume 12, Issue 1 , December 2012, Page 8-19

https://doi.org/10.33899/iphr.2012.62339

Abstract
  Objective: To evaluate the importance of combination of biochemical markers in patients with Acute Coronary Syndrome (ACS) and to determine the optimal biochemical strategy for highly sensitive, early diagnosis of myocardial injury. Patients and methods: This study was carried out in coronary care unit ...  Read More ...

Synthesis of new coumarin derivatives with suspected anticoagulant activity

Yasser Fakri Mustafa

Volume 12, Issue 1 , December 2012, Page 20-32

https://doi.org/10.33899/iphr.2012.62340

Abstract
  Objectives: To synthesize three series of new coumarin derivatives and to screen their anticoagulant activity in rabbits in order to define in more exact terms the structural features that responsible for the anticoagulant activity of coumarins. Methods: the first series was synthesized by esterification ...  Read More ...

Effect of typical and atypical antipsychotic drugs on serum C-reactive protein and lipid profile in schizophrenic patients

Faris A Ahmed

Volume 12, Issue 1 , December 2012, Page 33-40

https://doi.org/10.33899/iphr.2012.62341

Abstract
  Objectives: To assess the effect of quetiapine and fluphenazine on serum high sensitivity C-reactive protein (hs-CRP) and serum lipid profile in schizophrenic patients. Patients and methods: The subjects comprised two groups of twenty seven newly diagnosed schizophrenic patients for each group. The ...  Read More ...

Measurement of plasma cholinesterase activity in field workers

Ansam Naji Aboud Al-Haseni; Basil Mohammed Yahya

Volume 12, Issue 1 , December 2012, Page 41-47

https://doi.org/10.33899/iphr.2012.62342

Abstract
  Objectives: Measurement of cholinesterase (ChE) activity is considered as an important diagnostic tool in the cases of human poisoning with organophosphate (OP) and carbamate insecticides. Patients and methods: One hundred and seventy four subjects working in different fields and exposed to OP and carbamate ...  Read More ...

Alleviation of cisplatin-induced nephrotoxicity in rats by aqueous extract of Salvia officinalis leaves

Kawa Dizaye

Volume 12, Issue 1 , December 2012, Page 48-55

https://doi.org/10.33899/iphr.2012.62343

Abstract
  Objectives: To evaluate the protective effects of the aqueous extract of Salvia officinalis leaves against nephrotoxicity induced by cisplatin in rats. Methods: Albino rats were divided into three groups, each group consist of six rats. Group I treated with vehicle (distilled water) was kept as a control. ...  Read More ...

Effects of valsartan vs captopril on some renal function tests in hypertensive patients

Shamil Hashim Othman

Volume 12, Issue 1 , December 2012, Page 56-64

https://doi.org/10.33899/iphr.2012.62344

Abstract
  Objectives: To investigate the effects of valsartan and captopril on some renal function tests (RFTs) in patients with essential hypertension. Patients and methods: A total of 40 patients with stage I essential hypertension were recruited and investigated for RFTs which include, blood urea, serum creatinine, ...  Read More ...

Modified high performance liquid chromatographic method for the identification of chlordiazepoxide in animal blood

Zena Sattam Hamad; Basil Mohammed Yahya

Volume 12, Issue 1 , December 2012, Page 65-74

https://doi.org/10.33899/iphr.2012.62345

Abstract
  Objective: A method for simultaneous determination of chlordiazepoxide in rat plasma using liquid-liquid extraction followed by high performance liquid chromatography (HPLC) is described. Methods: The analytes were separated employing a LC-18 column (250mm×4.6mm,5µm) at ambient temperature using ...  Read More ...

Facial visible spectrophotometric determination of metformin hydrochloride in glucosam tablets and industrial waste water: Application to content uniformity testing

Nief Rahman Ahmad

Volume 12, Issue 1 , December 2012, Page 75-85

https://doi.org/10.33899/iphr.2012.62346

Abstract
  Objectives: To determine simple, accurate and highly sensitive spectrophotometric method for determination metformin hydrochloride in pharmaceutical preparations and in industrial waste water sample. Materials and Method: The method is based on the oxidation of metformin by a known excess of sodium ...  Read More ...