Mosul University
  • Register
  • Login
  • العربیة

Iraqi Journal of Pharmacy

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 13, Issue 2
  3. Author

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Peer Review Process

News

Guide to reviwers

Effect of atorvastatin in combination with different oral antidiabetic medications on lipid parameters and glucose level

    Mohammed N. Abed

Iraqi Journal of Pharmacy, 2013, Volume 13, Issue 2, Pages 62-69
10.33899/iphr.2013.86557

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Background: Dyslipidemia is common in patients with type 2 diabetes mellitus and is regarded as independent risk factor for cardiovascular disease.
The aim of this study was to evaluate the efficacy and safety of atorvastatin for the treatment of dyslipidemia in type 2 diabetics using either metformin or glibenclamide as oral hypoglycemic agents.
Materials and methods: Fourty five type 2 diabetic patients diagnosed with dyslipidemia met the study criteria and received 20 mg/day atorvastatin, then followed after 2 months. The various biochemical parameters studied included glycated hemoglobin (HbA1c), fasting serum glucose levels (FSG), total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, very low-density lipoprotein (VLDL) cholesterol and atherogenic index (AI).
Results showed that atorvastatin in both studied groups caused significant reduction in all measured parameters with an elevation in HDL, but this effect was obvious and more significant in patients using metformin than those using glibenclamide.
Conclusion: This study concluded that the combination of atorvastatin and metformin was more effective on lipid profile and glucose level than atorvastatin plus glibenclamide in type 2 diabetic patients with dyslipidemia.
Keywords:
    Dyslipidemia types diabetes mellitus atorvnstatin
  • PDF
  • XML
(2013). Effect of atorvastatin in combination with different oral antidiabetic medications on lipid parameters and glucose level. Iraqi Journal of Pharmacy, 13(2), 62-69. doi: 10.33899/iphr.2013.86557
Mohammed N. Abed. "Effect of atorvastatin in combination with different oral antidiabetic medications on lipid parameters and glucose level". Iraqi Journal of Pharmacy, 13, 2, 2013, 62-69. doi: 10.33899/iphr.2013.86557
(2013). 'Effect of atorvastatin in combination with different oral antidiabetic medications on lipid parameters and glucose level', Iraqi Journal of Pharmacy, 13(2), pp. 62-69. doi: 10.33899/iphr.2013.86557
Effect of atorvastatin in combination with different oral antidiabetic medications on lipid parameters and glucose level. Iraqi Journal of Pharmacy, 2013; 13(2): 62-69. doi: 10.33899/iphr.2013.86557
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 269
  • PDF Download: 118
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap
This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus