Mosul University
  • Register
  • Login
  • العربیة

Iraqi Journal of Pharmacy

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 13, Issue 1
  3. Author

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Peer Review Process

News

Guide to reviwers

Pattern of antibiotic sensitivity and resistance of uropathogenes among pediatric patients with urinary tract infection

    Ghayth M. AbdulRazzaq

Iraqi Journal of Pharmacy, 2013, Volume 13, Issue 1, Pages 64-76
10.33899/iphr.2013.66906

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Objectives: studying the microbiological profile by isolation of the types of bacteria that are most frequently causing UTI in pediatric patients and assessing the antibiotic resistance profile of 10 different antibiotics that are used for treatment of such infection. .
Methods: Urine samples from 900 symptomatic UTI cases attending Ibn Alatheer Teaching Hospital from May 2010 to September2011 were collected . Urinary isolates were identified by conventional methods and antibiotic resistance testing was performed by Kirby Bauer's disc diffusion method.
Results: We identify 6 species of uropathogens responsible for UTI in pediatric patients . Females are more susceptible to the UTI than males, however they usually infected by the same bacterial species. E. coli is the most predominant uropathogen in pediatric UTI. The isolated uropathogenes showed a heavy resistance pattern toward many antibiotics like Cotrimoxazole (84.1%) Amoxicilline(72.6%), Nalidixi acid(57.4%). Cephalosporin (particularly cefotaxime) , Augmentin, gentamycine and nitrofurantoin exhibit adequate antibiotic activity against uropathogens while Ciprofloxacin and Amikacine subjected to the least resistant pattern of commonly used antibiotics.
Conclusion: E. coli is still the most common type of bacteria causing UTI in male and female pediatric patients. Pediatric urine culture isolates are becoming increasingly resistant to commonly used antibiotics. Empirical treatment with Cotrimoxazole, Amoxicillin, or Nalidixic acid as initial drug is relatively ineffective. Cefotaxim and gentamycin can be considered as effective line for treatment of UTI . Amikacine and Ciprofloxacine are less likely to be subjected to drug resistance.
Keywords:
    urinary tract infection pediatrics urinary tract infection bacterial resistance
  • PDF
  • XML
(2013). Pattern of antibiotic sensitivity and resistance of uropathogenes among pediatric patients with urinary tract infection. Iraqi Journal of Pharmacy, 13(1), 64-76. doi: 10.33899/iphr.2013.66906
Ghayth M. AbdulRazzaq. "Pattern of antibiotic sensitivity and resistance of uropathogenes among pediatric patients with urinary tract infection". Iraqi Journal of Pharmacy, 13, 1, 2013, 64-76. doi: 10.33899/iphr.2013.66906
(2013). 'Pattern of antibiotic sensitivity and resistance of uropathogenes among pediatric patients with urinary tract infection', Iraqi Journal of Pharmacy, 13(1), pp. 64-76. doi: 10.33899/iphr.2013.66906
Pattern of antibiotic sensitivity and resistance of uropathogenes among pediatric patients with urinary tract infection. Iraqi Journal of Pharmacy, 2013; 13(1): 64-76. doi: 10.33899/iphr.2013.66906
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 312
  • PDF Download: 103
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap
This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus