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Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome

    Akram J Ahmad Samir B Al-Mukhtar

Iraqi Journal of Pharmacy, 2011, Volume 11, Issue 2, Pages 102-110
10.33899/iphr.2011.49916

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Abstract

Objectives: To compare between the qualitative estimation of biochemical markers
Point-of-Care testing) with the quantitative estimation of the same markers in the
diagnosis of acute coronary syndrome (ACS).
Design: Case-series study.
Setting: This study was carried out in coronary care unit in Ibn- Sena Teaching
Hospital in Mosul city from January to November, 2008.
Participant: Sixty five patients with acute coronary syndrome (ACS) presented with
chest pain.
Main outcome measures: Three cardiac markers (Creatine kinase (CK-MB)
activities (marker of necrosis), myoglobin (marker of muscle injury), and troponin I
(marker of necrosis), were estimated qualitatively (near the patient= Point-of-Care
testing), and quantitatively, and the results were compared. Kappa test was used for
the association between the quantitative and qualitative test results.
Results: The case-series study showed correlation of attributes between qualitative
estimation results of troponin I, myoglobin and CK-MB and quantitative estimation
results of the same parameters in (88.9%) tests.
Conclusion: The early diagnosis of ACS might be facilitated by the use of qualitative
point-of-care testing based on CK-MB, troponin I and myoglobin tests.
Keywords:
    Troponin I myoglobin MB activity Point Care Testing acute coronary syndrome Biochemical markers
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(2011). Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome. Iraqi Journal of Pharmacy, 11(2), 102-110. doi: 10.33899/iphr.2011.49916
Akram J Ahmad; Samir B Al-Mukhtar. "Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome". Iraqi Journal of Pharmacy, 11, 2, 2011, 102-110. doi: 10.33899/iphr.2011.49916
(2011). 'Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome', Iraqi Journal of Pharmacy, 11(2), pp. 102-110. doi: 10.33899/iphr.2011.49916
Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome. Iraqi Journal of Pharmacy, 2011; 11(2): 102-110. doi: 10.33899/iphr.2011.49916
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