Mosul University
  • Register
  • Login
  • العربیة

Iraqi Journal of Pharmacy

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 19, Issue 2
  3. Author

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Peer Review Process

News

Guide to reviwers

Preserving the Normal Healthy Testis: Role of Beta-carotene

    Abdulla A. Ahmad

Iraqi Journal of Pharmacy, 2022, Volume 19, Issue 2, Pages 74-83
10.33899/iphr.2022.176653

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Background: Many drugs can have significant deleterious side effects on the different organs of the body which can change normal physiology to different pathologies. Recent research have been focusing on valuable methods to preserve the normal healthy testis from the medications’ adverse effects. The study aims to investigate the role of beta-carotene in the protection against potential amikacin’s testicular toxicity.
Materials and methods: Male rats were involved in the study. Rats have divided into four groups: the first group was control, the second group has been given amikacin as an inducer of testicular toxicity; the third group has been given both amikacin and beta-carotene, and the fourth group has been given beta-carotene as prophylaxis before induction of the toxicity. The histological architecture of the testis was investigated for all the rats.
Results: Amikacin caused a significant deleterious effect which included degeneration and necrosis of cells of seminiferous tubules as well as atrophy and congestion of blood vessels. Co-administration of both beta-carotene and amikacin resulted in a partial improvement in the testicular tissue while using beta-carotene as prophylaxis succeeded in protecting and preserving the normal histological features of the testis completely.
Conclusion: The study concluded that beta-carotene can preserve the normal physiological testis and protect it against the amikacin’s deleterious effect on the testis.
Keywords:
    Beta-carotene Testis’s preservation seminiferous tubules
  • PDF (1759 K)
  • XML
(2022). Preserving the Normal Healthy Testis: Role of Beta-carotene. Iraqi Journal of Pharmacy, 19(2), 74-83. doi: 10.33899/iphr.2022.176653
Abdulla A. Ahmad. "Preserving the Normal Healthy Testis: Role of Beta-carotene". Iraqi Journal of Pharmacy, 19, 2, 2022, 74-83. doi: 10.33899/iphr.2022.176653
(2022). 'Preserving the Normal Healthy Testis: Role of Beta-carotene', Iraqi Journal of Pharmacy, 19(2), pp. 74-83. doi: 10.33899/iphr.2022.176653
Preserving the Normal Healthy Testis: Role of Beta-carotene. Iraqi Journal of Pharmacy, 2022; 19(2): 74-83. doi: 10.33899/iphr.2022.176653
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 32
  • PDF Download: 33
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap
This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus