Document Type : Review Paper


Department of Pharmacology, College of Pharmacy, University of Mosul, Mosul, Iraq.


Introduction Contraception is a method of avoiding unplanned pregnancy. Combined oral contraceptives (COCs) have become a prominent birth control method due to their contraceptive efficacy and acceptability profile. The use of oral contraceptive pills (OCPs) is linked to several health advantages as well as problems. Oral contraceptive pills can alter carbohydrate and lipid metabolism, including increased in blood glucose, triglyceride, low density lipoprotein LDL and total cholesterol. However, these changes may be affected by modification in type of progesterone used in oral contraceptive formulation.
Objective: the aim of this study is to evaluate the effect of oral contraceptives on glucose levels and lipid profile by emphasizing many studies that show the effect of oral contraceptive pills on the metabolic parameters such as (Fasting serum glucose, HbA1c%, total cholesterol, LDL, HDL and triglyceride level).