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Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials

    Rahma M. Jebir Yasser F. Mustafa

Iraqi Journal of Pharmacy, 2021, Volume 18, Issue 2, Pages 139-161
10.33899/iphr.2022.170404

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Abstract

Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial, anticoagulant, antihypertensive, anticancer, antioxidant, anti-inflammatory, and many other medicinal potentials. Because coumarins are found in nuts, seeds, fruits, vegetables, tea, coffee, and wine, the average person consumes a significant amount of these substances daily. Given the documented limited toxicity, relatively cheap, availability in foods, and prevalence of coumarins in numerous herbal medicines, it seems reasonable to investigate their characteristics and usage.
Objective: This review discusses naturally occurring coumarin lead substances, their extensive medicinal benefits, and official pharmacopoeia-based detection methods.
Conclusion: The medicinal potential and therapeutic uses of simple coumarins are determined by their structural substitution pattern. Because there is limited research on bioavailability for coumarins, additional research is needed to investigate the bioavailability for various coumarins, which have demonstrated good bioactivity in prior research.
Keywords:
    Natural Coumarins antibacterial Antiviral Antihypertensive Anticonvulsant
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(2022). Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials. Iraqi Journal of Pharmacy, 18(2), 139-161. doi: 10.33899/iphr.2022.170404
Rahma M. Jebir; Yasser F. Mustafa. "Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials". Iraqi Journal of Pharmacy, 18, 2, 2022, 139-161. doi: 10.33899/iphr.2022.170404
(2022). 'Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials', Iraqi Journal of Pharmacy, 18(2), pp. 139-161. doi: 10.33899/iphr.2022.170404
Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials. Iraqi Journal of Pharmacy, 2022; 18(2): 139-161. doi: 10.33899/iphr.2022.170404
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