Pharmaceutics & Industrial Pharmacy
Scanning Sildenafil Citrate Solubility in Hydrotropic Solutions

Ebtissam Ameer Al-dulaimi; Mohanad Alfahad; Mohannad Emad Qazzaz

Volume 20, Issue 2 , December 2023, , Page 79-82

https://doi.org/10.33899/iphr.2023.140337.1045

Abstract
  Background: Sildenafil citrate (SC) is a selective phosphodiesterase-5 inhibitor with low aqueous solubility (4.1 mg/mL in water), resulting in only 40% bioavailability after oral administration. SC is classified as class II by the Biopharmaceutical Drug Classification System. Hydrotropic agents are ...  Read More ...

Pharmaceutics & Industrial Pharmacy
Cell Line Culture in Pharmaceutical Development and Application: A Review

Zainab Eassa Jassim

Volume 20, Issue 1 , June 2023, , Page 17-22

https://doi.org/10.33899/iphr.2023.138155.1023

Abstract
  Background: The use of conventional animal testing to determine how medications affect a biological system comes with many challenges. In recent years, a variety of techniques to achieve these goals were presented, one of these is cell line creation technology that has dramatically increased in usefulness ...  Read More ...