Official Journal of the College of Pharmacy, University of Mosul
Pharmaceutical Chemistry
Synthesis and Pharmacological Profiles of 6,7-Dihydroxycoumarin and Its Derivatives: A Concise Review

Nameer Mazin Zeki; Yasser Fakri Mustafa

Volume 20, Supplementary Issue 1 , December 2023, , Page 174-188

https://doi.org/10.33899/iphr.2023.143017.1059

Abstract
  Background: Esculetin, scientifically referred to as 6,7-dihydroxycoumarin, functions as the primary bioactive constituent found in Cortex Fraxini (commonly known as ash bark), an ancient Asian medicinal substance. Herbal practitioners utilize the outer layer of the branch or stem bark of Cortex Fraxini ...  Read More ...

Pharmaceutical Chemistry
Thermosonication-Catalyzed Synthesis of New 3-Esterified Coumarins as Biocompatible Antitumor Candidates

Sawsan Hasan Hammodi

Volume 20, Supplementary Issue 1 , December 2023, , Page 236-242

https://doi.org/10.33899/iphr.2023.144182.1066

Abstract
  Background: Coumarin chemical moiety and its-based molecules attracted a lot of research attention by chemists of natural products and organic synthesis. This attention works in two directions: synthetic approaches and biological activities. Methods: In this work, salicylaldehyde was condensed via a ...  Read More ...

A review on coumarin backbone: An attractive scaffold for promising bioactive compounds

Sara F. Jasim; Yasser F. Mustafa

Volume 18, Issue 2 , December 2021, , Page 104-125

https://doi.org/10.33899/iphr.2022.170402

Abstract
  Background: Coumarin moiety is found in many naturally occurring products that have been used for many decades in traditional medicine around the world. Coumarin has distinctive physicochemical properties and can be easily transformed into a wide range of functionalized coumarins. As a result, a large ...  Read More ...

Synthesis of coumarin-based derivatives from different starting materials: A review of ongoing developments

Sarah A. Waheed; Yasser F. Mustafa

Volume 18, Issue 2 , December 2021, , Page 126-138

https://doi.org/10.33899/iphr.2022.170403

Abstract
  Objective: This brief review highlights the recent advances in the synthesis of coumarin-based derivatives from phenols, aldehydes, ketones, and various other functional group-containing starting compounds. Also, the recent developments in the conditions of several original synthetic methods involving ...  Read More ...

A review on the antibacterial potential of cantabiline-based derivatives

Noora T. Abdulaziz; Yasser F. Mustafa

Volume 17, Issue 1 , January 2020, , Page 93-114

https://doi.org/10.33899/iphr.2020.167600

Abstract
  Objective: The target of this review study is to highlight the importance of cantabiline and its derived compound as antibacterial agents. Also, to take into consideration the characteristic structural features that can enhance the capability of these compounds to fight pathogenic bacteria.Methods: The ...  Read More ...