Design, synthesis, and evaluation the anti-β-lactamase activity of new sulphathiazole-derived monobactam compounds

Ahmed A. J. Mahmood; Mohammed A. Al-Iraqi; Faris T. Abachi

Volume 17, Issue 1 , January 2020, , Page 19-36

https://doi.org/10.33899/iphr.2020.167596

Abstract
  Objectives: β-Lactams are the most successful antibiotics for the management of infectious diseases. Unfortunately, the bacterial production of β-lactamase that hydrolyzes the β-lactam ring can inactivate these drugs. The use of β-lactamase inhibitors like (clavulanic acid) in combination ...  Read More ...