Synthesis of new metoclopramide derivatives and in vitro evaluation of their human cholinesterases protection against Chlorpyrifos

Islam Tarik Qasim; Ahmed A.J. Mahmood; Yasser Fakri Mustafa

Volume 11, Issue 2 , December 2011, , Page 58-69

https://doi.org/10.33899/iphr.2011.49900

Abstract
  Objective: The purpose of this study was to synthesize three new derivatives of metoclopramide by diazotization and replacement reactions and then to quantify in vitro their protection effects on blood cholinesterases using chlorpyrifos as a potent inhibitor. methods: The three new metoclopramide ...  Read More ...