Pharmaceutical Chemistry
Yasser Fakri Mustafa; Sarah Ahmed Waheed; Sara Firas Jasim; Rahma Mowaffaq Jebir; Reem Nadher Ismael; Omar Qutachi
Abstract
Background: Coumarins and their derivatives excel in chemical diversity, coupled with a wide variety of biological potentials, and tend to be beneficial to the health of the human body. One of these derivatives that has sparked the attention of medicinal chemistry specialists in recent decades is benzo-fused ...
Read More ...
Background: Coumarins and their derivatives excel in chemical diversity, coupled with a wide variety of biological potentials, and tend to be beneficial to the health of the human body. One of these derivatives that has sparked the attention of medicinal chemistry specialists in recent decades is benzo-fused coumarins, which have demonstrated their potential as antioxidants, antimicrobials, antidiabetics, antithrombotics, and many more. Objective: This paper discusses the medicinal importance of benzo-fused coumarins derived from natural or synthetic sources. Conclusion: The researchers documented that benzo-fused coumarin's basic structure is a promising framework that opens up the chance of discovering innovative applicants with advanced therapeutic potentials.
Ahmed A. Mahmood; Mohammed A. Al-Iraqi; Faris T. Abachi
Abstract
Objective:To evaluate the role of fluorine atom in modern drug synthesis. Methods: Different types of fluorinated were prepared, antimicrobials, antivirals, F-NSAIDs, peptides and protein synthesis. Results: Recent developments and future prospects of fluorine in medicinal chemistry and chemical ...
Read More ...
Objective:To evaluate the role of fluorine atom in modern drug synthesis. Methods: Different types of fluorinated were prepared, antimicrobials, antivirals, F-NSAIDs, peptides and protein synthesis. Results: Recent developments and future prospects of fluorine in medicinal chemistry and chemical biology. The extraordinary potential of fluorine - containing biologically relevant molecules in antimicrobial or antivirial agents, or peptide or protein chemistry, medicinal chemistry, chemical biology, pharmacology, and drug discovery as well as diagnostic and therapeutic applications, was recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of fluorine chemistry has been rapidly expanding its biomedical frontiers. Conclusion: This review how to list of fluorinated drugs( Antimicrobial agents , anticancer agents, Antiviral agents, and study their physicochemical properties of fluorine drugs.