Design, synthesis, and evaluation the anti-β-lactamase activity of new sulphathiazole-derived monobactam compounds

Ahmed A. J. Mahmood; Mohammed A. Al-Iraqi; Faris T. Abachi

Volume 17, Issue 1 , January 2020, , Page 19-36

https://doi.org/10.33899/iphr.2020.167596

Abstract
  Objectives: β-Lactams are the most successful antibiotics for the management of infectious diseases. Unfortunately, the bacterial production of β-lactamase that hydrolyzes the β-lactam ring can inactivate these drugs. The use of β-lactamase inhibitors like (clavulanic acid) in combination ...  Read More ...

Investigation of some bioactive compounds in oil and ethanol extracts of ginger (Zingerbiene officlica) using GC-MS

Faris T. Abachi; Khadeeja Younus; Inas Hazim

Volume 16, Issue 1 , July 2019, , Page 22-35

https://doi.org/10.33899/iphr.2019.165707

Abstract
  Objective: The molecular characterization of some bioactive compounds in ginger interest because of their various pharmacological activities.  To the best of our knowledge, we are isolate hydrocarbon (low molecular weight), alcohol, phenol, acid, ester from nonpolar (oil) and polar (ethanol) extracts ...  Read More ...

Fluorine important element in new drugs synthesis: Review Study

Ahmed A. Mahmood; Mohammed A. Al-Iraqi; Faris T. Abachi

Volume 15, Issue 1 , January 2018, , Page 37-45

https://doi.org/10.33899/iphr.2018.164169

Abstract
  Objective:To evaluate the role of fluorine atom in modern drug synthesis. Methods:  Different types of fluorinated were prepared, antimicrobials, antivirals, F-NSAIDs, peptides and protein synthesis. Results: Recent developments and future prospects of fluorine in medicinal chemistry and chemical ...  Read More ...