Pharmacology and Toxicology
Drug-Induced Liver Injury: Mechanisms and Counteracting Herbal-Derived Products

Doha Ismail Alrawi; Musab Mohammed Khalaf; Mohammed Khalid Jamaludeen

Articles in Press, Accepted Manuscript, Available Online from 08 March 2024

https://doi.org/10.33899/iraqij.p.2024.145444.1078

Abstract
  Background: Exposure to both synthetic and naturally occurring chemical substances can cause a wide range of reactions such as Drug-Induced Liver Injury(DILI). It is a serious problem due to the increasing number of substances being used for the treatment of different illnesses, coupled with the growing ...  Read More ...

Pharmacology and Toxicology
A Comprehensive View on Drugs-Induced Cardiotoxicity and Its Prevention

Abdulnaser Ahmad Ali; Musab Mohammed Khalaf; Abdulla A. Ahmad

Volume 21, Issue 1 , March 2024, , Page 20-35

https://doi.org/10.33899/iphr.2024.145016.1070

Abstract
  Background: The prevention of drug-induced cardiotoxicity is a complicated challenge facing healthcare providers during the last few decades. This challenge is raised from the unclear definition of the term “cardiotoxicity”, the overlapping of the symptoms of heart dysfunction due to the ...  Read More ...

The Protective Effect of Milk Thistle Against Drug-Induced Renal Illnesses: A Review

Noor A. Abed; Musab M. Khalaf; Mohammed Kh. Alnori

Volume 19, Issue 2 , December 2022, , Page 93-107

https://doi.org/10.33899/iphr.2022.176655

Abstract
  Introduction:  Nephrotoxicity is one of the most frequent kidney problems and happens when the body becomes exposed to medicine or toxin. Because renal tubular cells have metabolic activities, nephrotoxin can produce toxic components and cause damage. Paracetamol drug is safe when taken in therapeutic ...  Read More ...

In-vitro Examination of The Potential Antibacterial Activity of Simvastatin

Hani Almukhtar; Hiyam A. Altaii; Musab M. Khalaf

Volume 17, Issue 1 , January 2020, , Page 75-92

https://doi.org/10.33899/iphr.2020.167599

Abstract
  Background: Statins are group of medicines that block mevalonate pathway by competitive inhibition of the rate limiting enzyme hydroxy-methylglutaryl-CoA reductase (HMG-CoA). Statins additionally inhibit the biosynthesis of important isoprenoid intermediates which have a role in peptidoglycan synthesis ...  Read More ...

Pulmonary surfactant in COVID-19; A role in etiology and treatment

Myasar Alkotaji; Musab M. Khalaf

Volume 17, Issue 1 , January 2020, , Page 115-134

https://doi.org/10.33899/iphr.2020.167601

Abstract
  Introduction: Today, SARS-COV-2 infection represents a global threat. Dealing with this viral infection necessitates a comprehensive understanding of pathophysiology of the disease to reach to the suitable treatment. Treatment of this disease should not be restricted to the usual antiviral treatments, ...  Read More ...