Preparation of modified release diltiazem HCl capsule by complexation with ion exchange resin

Eman B.H. Al-Khedairy; Alaa A. Abdulrasso; Jenan M. AL-Mosawi

Volume 11, Issue 2 , December 2011, , Page 17-26

https://doi.org/10.33899/iphr.2011.49655

Abstract
  Background: Diltiazem HCl is a calcium channel blocker drug used in the treatment of angina pectoris and hypertension. Objective: To prepare a sustained release diltiazem HCl capsule by complexation with polystyrene sulfonate strong cation exchange resin (dowex®50wx4) as a complexing and retarding ...  Read More ...